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Prostate Needle Biopsy

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You and your urologist may decide to proceed with a biopsy of the prostate. During the biopsy a small sample of prostate tissue is collected for a pathologist to examine under a microscope. Reasons for having a prostate needle biopsy include an elevated prostate specific antigen (PSA) or abnormal digital rectal exam (DRE).

Prior to the procedure

Before the procedure you will be asked to stop certain blood thinners and anti-inflammatory medications. You may be started on an antibiotic medication. Please call your urologist if you think you have a urinary tract infection.

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Following the procedure

  • Expect to have some blood in your urine and some discomfort with urination. This generally lasts only a day or two but may persist beyond that time period depending on the extent of the procedure.
  • You will be given an oral antibiotic to prevent infection. Please read the prescription bottle and follow these instructions exactly.
  • You may be given a medication to help with bladder discomfort and burning on urination. These medications are best taken with food and some may color the urine orange.
  • Drink extra fluids the first day or two after the procedure, as it will clear any bleeding and help prevent infection.
  • If you experience difficulty emptying your bladder, excessive pain or temperature greater than 100 degrees, call your physician immediately. Our staff is available 24 hours a day, seven days a week.

It takes approximately 7-10 days to obtain the final biopsy results with your pathologist. Your urologist will discuss the biopsy results with you at your follow-up appointment.

Physicians performing this procedure: